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Breast Cancer and High Bone Density:
Overlooked Links

In addition to blood clots, numerous studies show that patients with breast cancer also have higher than normal bone density. While we know that low bone density is problematic and can lead to fractures, perhaps having very dense bones is not an indicator for an ideal state of health either.

Studies linking high bone mineral density to breast cancer include:

Aspirin and Lower Bone Densities

Aspirin, which as noted in the preceding sections, is preventative against blood clots and breast cancer, and blocks vitamin K, has also been shown to reduce bone mass in rats. In a 1986 study, researchers studied the effect of acetylsalicylic acid (aspirin) on bone metabolism in young male rats. The results indicated "an inhibitory effect of ASA (acetylsalicylic acid) on bone resorption and formation in growing rats."

Vitamin K: Can Excessive Levels Be a Factor in Breast Cancer?

Vitamin K promotes blood clotting, osteocalcin, MGA proteins, and high bone mineral density. Patients with breast cancer tend to have blood clots, high levels of osteocalcin, MGA proteins, and high bone mineral density, the same conditions caused by high levels of vitamin K. Substances known to be effective against breast cancer include olive oil, garlic, aspirin and vitamin E. These are all substances that thin the blood and/or block vitamin K. Which leads to the question, "Are high levels of vitamin K a factor in breast cancer?" I think it is a question worth considering.

The charts below show that many of the factors that are known to increase the risk of breast cancer are the same factors that are linked to increased vitamin K levels. Conversely, many of the factors linked to a reduced risk of breast cancer are identical to the factors linked to vitamin K deficiencies. The table below illustrates some of the common factors found between high levels of vitamin K and breast cancer.

Factors linked to high levels of vitamin K
Factors linked to breast cancer

Increased coagulation

Improved bone density

Low vitamin E levels

Elevated levels of Gla protein


Increased coagulation

Improved bone density

Low vitamin E levels

Elevated levels of Gla protein


Factors linked to both high levels of Vitamin K and increased rates of breast cancer

Since a number of the factors that have been linked to increased breast cancer risks have also been linked to increased levels of vitamin K, it may be logical to consider the possiblity that the conditions themselves are closely linked. We already know many of the conditions that can reduce vitamin K levels, and it may be logical to use some of this information in searching for additional factors that would be preventative against breast cancer.

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