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Magnesium Deficiency in Multiple Sclerosis

The MS-Magnesium Connections

Symptoms of MS that are also symptoms of magnesium deficiency include muscle spasms, weakness, twitching, muscle atrophy,  an inability to control the bladder, nystagmus (rapid eye movements), hearing loss, and osteoporosis.  People with MS have higher rates of epilepsy than controls.  Epilepsy has also been linked to magnesium deficiencies.

Here are some interesting studies on multiple sclerosis and magnesium: 

  •  In a 1995 paper published in the journal Acta Neurologica Scandinavica, patients with multiple sclerosis were found to be low in cellular magnesium. 1


Personal Observations

I personally have a related condition to MS called Ehlers-Danlos syndrome that has many overlapping features with MS. Over the years I have been able to control many of my symptoms with proper diet. During a recent relapse I had nutritional testing done again and was found to be low in magnesium, along with several other nutrients that are often linked to MS symptoms, such as vitamin B12 and vitamin D.

Related Pages:


1. Stelmasiak Z, Solski J, Jakubowska B. Magnesium concentration in plasma and erythrocytes in MS. Acta neurologica Scandinavica, 1995 Jul;92(1):109-11

2. Altura BT, Bertschat F, Jeremias A, Ising H, Altura BM. Comparative findings on serum IMg2+ of normal and diseased human subjects with the NOVA and KONE ISE's for Mg2+. Scandinavian journal of clinical and laboratory investigation. Supplementuml. 1994;217:77-81

3. Yasui M, Yase Y, Ando K, Adachi K, Mukoyama M, Ohsugi K. Magnesium concentration in brains from multiple sclerosis patients. Acta neurologica Scandinavica. 1990 Mar;81(3):197-200.

4. Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Medical Hypotheses. 1986 Oct;21(2):193-200.

5. P. Rossier, S. van Erven and D. T. Wade. The effect of magnesium oral therapy on spasticity in a patient with multiple sclerosis . European Journal of Neurology Volume 7 Page 741 - December 2000 doi:10.1046/j.1468-1331.2000.00142.x Volume 7 Issue 6


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